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6-dicarboxamide tris(2
Additional water is eliminated by osmotic diuresis
CAS Number: 1346604-70-3
PKACα and PKC
PAP-1 ethylcarbamazine citrate 6-dicarboxamide tris(2SPS 4251, also known as AS 77 and PAP 1, is a KCNA3 (Potassium voltage gated channel, shaker related subfamily, member 3) channel blocker potentially for the treatment of plaque psoriasis. Kv1. 3 channels regulate the activation proliferation of effector memory T cells and thus play a critical role in the pathogenesis of autoimmune diseases. PAP 1 reduced the secretion of TNF by adipose tissue but had no effect on the secretion of IL 6. PAP 1 can also
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