Afatinib D6 Catalog No.:M28317-C Smiles: O=C(NC1=CC=CN=N1)N1CCC(CC1)=CC1=CC(=CC=C1)OC1=CC=C(C=N1)C(F)(F)F

Smiles: O=C(NC1=CC=CN=N1)N1CCC(CC1)=CC1=CC(=CC=C1)OC1=CC=C(C=N1)C(F)(F)F

41 nM (Fyn)

consistent with our intermediate exchange resonance broadening by PrOF NMR

ClH/c17-12-3-1-2-11-8-14(21-15(11)12)16(20)18-13-9-19-6-4-10(13)5-7-19

Afatinib D6 Catalog No.:M28317-C Smiles: O=C(NC1=CC=CN=N1)N1CCC(CC1)=CC1=CC(=CC=C1)OC1=CC=C(C=N1)C(F)(F)FAfatinib D6 (BIBW 2992 D6) is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor. Product information CAS Number: 1313874 96 2 Molecular Weight: 491. 98 Formula: C24H25ClFN5O3 Chemical Name: (2E) N {4 [(3 chloro 4 fluorophenyl)amino] 7 [(3S) oxolan 3 yloxy]quinazolin 6 yl} 4 [di(H)methylamino]but 2 enamide Smiles: [2H]C([2H])([2H])N(C C=C