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β-Naphthoflavone-CH2-OH Catalog No.:M15296-2 h]cycloocta[jkl]cyclopenta[e]-as-indacene-7-carboxylic acid

SKU: 42342667513

4.3
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Description

h]cycloocta[jkl]cyclopenta[e]-as-indacene-7-carboxylic acid

Smiles: CC(NC(=O)C(CCC(O)=O)NC(=O)CNC(=O)C(N)CC(O)=O)C(O)=O

InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2

InChiKey: BQNXBSYSQXSXPT-UHFFFAOYSA-N

β-Naphthoflavone-CH2-OH Catalog No.:M15296-2 h]cycloocta[jkl]cyclopenta[e]-as-indacene-7-carboxylic acidNaphthoflavone CH2 OH ( NF CH2 OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. Naphthoflavone CH2 OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e. g., naphthoflavone JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination mediated degradation of cancer promoting proteins . Product information Molecular Weight: 302. 32

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