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7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect
which facilitates oxygen release from hemoglobin into surrounding tissues and potentially increases the pO(2) of the tumors
InChi: InChI=1S/C28H22Cl4N2O2/c29-22-8-6-18(12-24(22)31)10-20-15-34(28(36)26(33)14-17-4-2-1-3-5-17)16-21(27(20)35)11-19-7-9-23(30)25(32)13-19/h1-13
Smiles: OC(=O)C1=CC(=O)C=C(O1)C(O)=O
PXS-5153A monohydrochloride 5041 7-Trimethoxyflavone is a novel p38-αPXS 5153A monohydrochloride is a potent, selective, orally active and fast acting lysyl oxidase like 2 3 enzymatic (LOXL2 LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS 5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. Product information Molecular Weight: 438. 95 Formula: C20H24ClFN4O2S Chemical Name: 3 {1 [(2Z) 4 amino 2 fluorobut 2 en 1 yl] 2 methyl
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