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PTP Inhibitor IV - CAS# 329317-98-8 Catalog No.:M23057-C PubMed Central PMCID: PMC5218466

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PubMed Central PMCID: PMC5218466

CN(C)C1C=CC(=CC=1)C1NC2=CC=C(C=C2N=1)C1NC2=CC=C(C=C2N=1)N1CCN(C)CC1

The binding affinity of SJM-3 at wild type receptors is determined by displacement of [3H]-Flunitrazepam and [3H]-Ro15-1788 and indicates a Ki of SJM-3 amounting to 218±70 nM and 242±38 nM

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PTP Inhibitor IV - CAS# 329317-98-8 Catalog No.:M23057-C PubMed Central PMCID: PMC5218466IC50: 1. 8, 2. 5, 8. 4, 13, 20, 6. 4, and 6. 7 M for SHP 2, PTP1B, PTP , PTP Meg 2, PTP , PTP , and PTP , respectively PTP Inhibitor IV is a protein tyrosine phosphatases (PTPs) inhibitor. PTPs are reported to be important in the regulation of various signal transduction processes. Enzymes of this class are considered as potential therapeutic targets in the treatment of various diseases including inflammation, diabetes, as well as cancer. However,

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