6 μM for PFKFB3 and PFKFB4
InChi: InChI=1S/C24H26N6O2S/c1-28-13-15-29(16-14-28)20-6-3-5-19(17-20)25-24-26-23-22(7-4-12-30(23)27-24)18-8-10-21(11-9-18)33(2
In vitro studies show that GNE-781 reduces FOXP3 (forkhead box P3) transcript levels with a less optimal chemical probe
both in a dose-dependent manner
1α, 25-Dihydroxy VD2-D6 - CAS# 216244-04-1 min D4 6 μM for PFKFB3 and1alpha, 25 Dihydroxy VD2 D6 is a deuterated form of vitamin D. Product information CAS Number: 216244 04 1 Molecular Weight: 434. 68 Formula: C28H44O3 Chemical Name: (1R,3S,5Z) 5 {2 [(1R,3aS,4E,7aR) 1 [(2R,3E,5S) 6 hydroxy 6 (H)methyl 5 methyl(7,7,7 H)hept 3 en 2 yl] 7a methyl octahydro 1H inden 4 ylidene]ethylidene} 4 methylidenecyclohexane 1,3 diol Smiles: [2H]C([2H])([2H])C(O)([C@@H](C) C=C [C@@H](C)[C@H]1CC[C@H]2 C( CCC[C@@]21C)=C C=C1