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4SC-202 has very high selectivity over ClassIIa/IIb/III HDACs
stimulates periosteal bone formation in monkeys
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
CAS Number: 1956356-56-1
Rapamycin - mTOR inhibitor. CAS# 53123-88-9 size:2mg solid 4SC-202 has very high selectivityRapamycin, CAS No. 53123 88 9, is a potent and selective mTOR inhibitor. Rapamycin, in complex with the cytosolic protein FK binding protein 12 (FKBP12), inhibits mTOR Complex 1 (mTORC1) by binding to the FRB domain of mTor. Given the central roles mTor plays, Rapamycin showed diverse activities, including anti proliferative effects in cancer cells, immunosuppressive effect, lifespan extension in mice, improved cognition in the mouse model of autism
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