Talabostat Catalog No.:M19987-C 0 nM in IMR-32 cells

0 nM in IMR-32 cells

7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one

angiotensin II acts at the Na/H exchanger in the proximal tubules of the kidney to stimulate Na reabsorption and H excretion which is coupled to bicarbonate reabsorption

Formula: C57H65F5N10O8

Talabostat Catalog No.:M19987-C 0 nM in IMR-32 cellsTalabostat (Val boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP IV) inhibitor (IC50 < 4 nM; Ki = 0. 18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8 9 (IC50 = 4 11 nM; Ki = 1. 5 0. 76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis stimulating activities. Product