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ZCL278 directly binds to the binding site of the Cdc42 guanine nucleotide exchange factor intersectin (ITSN) and inhibits its functions (Kd ~6-11 µM)
IPA-3 treatment significantly inhibited the growth of HCC cells
modest effect on MYC and PIM1 expression
also known as E7010
Diatrizoic acid - CAS# 117-96-4 elate ZCL278 directly binds to theDiatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium. Product information CAS Number: 117 96 4 Molecular Weight: 613. 91 Formula: C11H9I3N2O4 Synonym: Diatrizoate Amidotrizoic acid Chemical Name: 3, 5 diacetamido 2, 4, 6 triiodobenzoic acid Smiles: