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Solamargine - CAS# 20311-51-7 Catalog No.:M9872-10 Formula: C16H13N4NaO3S

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Description

Formula: C16H13N4NaO3S

2015 Apr 23

4-dihydroisoquinolin-2(1 h)-yl)methanone

Chemical Name: (Z)-7-[(1R

Solamargine - CAS# 20311-51-7 Catalog No.:M9872-10 Formula: C16H13N4NaO3SSolamargine is a glycoalkaloid that has been found in S. lycocarpum and has anticancer activity. It decreases viability of H1650, H1975, PC 9, A549, and H1299 non small cell lung cancer (NSCLC) cells. Solamargine increases ERK1 2 phosphorylation and decreases the expression of DNA methyltranferase 1 (DNMT1) in H1299 and A549 cells. It reduces tumor growth and increases ERK1 2 phosphorylation and reduces the expression of the prostaglandin E2 receptor,

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