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Van De Kerkhove C
5 and 20 μM) in human platelet-rich plasma with IC50 values of 0
CAS Number: 1849603-72-0
brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics
I-OMe-Tyrphostin AG 538 Catalog No.:M25719-C Van De Kerkhove CI OMe Tyrphostin AG 538 (I OMe AG 538) is a specific inhibitor of IGF 1R (insulin like growth factor 1 receptor tyrosine kinase). I OMe Tyrphostin AG 538 inhibits IGF 1R mediated signaling and is preferentially cytotoxic to nutrient deprived PANC1 cells. I OMe Tyrphostin AG 538 is an ATP competitive inhibitor of phosphatidylinositol 5 phosphate 4 kinase (PI5P4K), with an IC50 of 1 M. Product information CAS Number: 1094048 77 7 Molecular Weight: 437.
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