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PF-4840154 ydroxy-2-naphthoic acid InChiKey: KAJXOWFGKYKMMZ-UHFFFAOYSA-N

SKU: 46916585382

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Description

InChiKey: KAJXOWFGKYKMMZ-UHFFFAOYSA-N

InChi: InChI=1S/C27H26N4O2S/c1-30-23-15-8-7-14-22(23)29-27(30)34-18-25(32)31-17-9-16-24(31)26(33)28-21-13-6-5-12-20(21)19-10-3-2-4-11-19/h2-8

Overcoming the resistance to crizotinib in patients with non-small cell lung cancer harboring EML4/ALK translocation

Menadione sodium bisulfite (500 μM) treatment and the concomitant ROS increase have an important impact on the photosynthetic activity of the cells

PF-4840154 ydroxy-2-naphthoic acid InChiKey: KAJXOWFGKYKMMZ-UHFFFAOYSA-NPF 4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC50s of 97 and 23 nM, respectively. PF 4840154 elicits TrpA1 mediated nocifensive behaviour in mouse. Product information CAS Number: 1332708 14 1 Molecular Weight: 466. 62 Formula: C26H38N6O2 Chemical Name: N benzyl 4 [(2 methylpropyl)amino] 2 {4 [(oxan 3 yl)methyl]piperazin 1 yl}pyrimidine 5 carboxamide Smiles: CC(C)CNC1=NC(=NC=C1C(=O)NCC1=CC=CC=C1)N1CCN(CC2COCCC2)CC1

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