![Euphorbia Factor L1 Catalog No.:M13963-2 Chemical Name: N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M13963_1631088089.gif?v=1631088092)
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Chemical Name: N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1
Formula: C26H43Cl3N4
Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages
0 μM) and Mcl-1 (IC50
Euphorbia Factor L1 Catalog No.:M13963-2 Chemical Name: N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1Euphorbia Factor L1 is a diterpenoid from Euphorbia lathyris L., reduces the expression of Bcl 2, PI3K, AKT and mTOR protein and mRNA, upregulates cleaved caspase 9 and caspase 3 levels, buts shows no effect on pro caspase 9 and pro caspase 3. Euphorbia Factor L1 induces apoptosis, has anticancer, antiadipogenesis, antiosteoclastogenesis and multidrug resistance modulating effect. Product information CAS Number: 76376 43 7 Molecular Weight: 552. 66