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4-dimethoxyphenyl)-4-methoxy-7
K00546 binds to the SLK ATP-binding site forming three hydrogen bonds with the kinase hinge residues E109 and C111
InChi: InChI=1S/C25H39N3O5/c1-16(2)12-20(14-29)26-23(30)21(13-17(3)4)27-24(31)22(18(5)6)28-25(32)33-15-19-10-8-7-9-11-19/h7-11
OUN67600 was first reported by Atobe et al (compound 36 in J Med Chem
Kanamycin A Size:Contact [email protected] for quotation 4-dimethoxyphenyl)-4-methoxy-7Kanamycin A is a broad spectrum antibiotic. Kanamycin A was first isolated in 1957 by Hamao Umezawa from the bacterium Streptomyces kanamyceticus. In vitro: In previous study, kanamycin A was found to block a single cycle of translocation on the poly[U] ribosome, carrying N acetyl diPhe tRNA on the acceptor site and deacylated tRNA at the donor site. The GTPase reaction, catalyzed by EF G and ribosomes, was not significantly affected by kanamycin A.
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