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Chemical Name: (6S)-9-hydroxy-5
TMC207 fumarate
Gene expression studies performed on tibialis samples revealed that both GLPG0492 was slowing down muscle loss by negatively interfering with major signaling pathways controlling muscle mass homeostasis
after oral administration
KRAS G12D inhibitor 1 - CAS# 2621928-43-4 563 hydrochloride Chemical Name: (6S)-9-hydroxy-5KRAS G12D inhibitor 1 (example 243) is a KRAS G12D inhibitor, with an IC50 of 0. 8 nM for KRAS G12D mediated ERK phosphorylation. Product information CAS Number: 2621928 43 4 Molecular Weight: 582. 64 Formula: C33H32F2N6O2 Chemical Name: 4 (2 {[(2R, 7aS) 2 fluoro hexahydro 1H pyrrolizin 7a yl]methoxy} 4 {3, 8 diazabicyclo[3. 2. 1]octan 3 yl} 8 fluoropyrido[4, 3 d]pyrimidin 7 yl) 5 ethynylnaphthalen 2 ol Smiles:
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