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InChiKey: DDVJEYDLTXRYAJ-UHFFFAOYSA-N
Cadazolid levels persists at 50-100-fold supra-MIC for 14 days post-dosing
TJ191 induces the maximum apoptotic rate of 80% after 24 h
6-dichlorobenzamide
AZ 12080282 dihydrochloride 2653 InChiKey: DDVJEYDLTXRYAJ-UHFFFAOYSA-NAZ 12080282 dihydrochloride is a selective inhibitor of Hh with IC50 value <0. 012 M . It is also reported that AZ 12080282 also has a selective inhibition to p38 with low nanomolar potency . Hedgehog (Hh) signaling plays an important role in a wide variety of developmental processes, including larval body segment development and adult appendages formation. Abnormal activation of Hh pathway may lead to developmental disease by transforming adult stem
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