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AZD3839 free base - CAS# 1227163-84-9 2302 Actein has little toxicity in

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Description

Actein has little toxicity in vivo

41(5):1192-9

and can also halt glucose entry by insulin in adipocytes

2017 Dec 9

AZD3839 free base - CAS# 1227163-84-9 2302 Actein has little toxicity inAZD3839 free base is a potent and selective orally active, brain permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000 fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose and time dependent lowering of plasma, brain, and cerebrospinal fluid A levels in mouse, guinea pig, and non human primate. AZD3839 free base can be used for the research of Alzheimer's disease. Product information CAS

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