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STAT3-IN-3 - CAS# 2361304-26-7 Catalog No.:M12094-10 CK-636 inserts into the hydrophobic

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Description

CK-636 inserts into the hydrophobic core of Arp3 and alters its conformation

Small molecule inhibitors of the BMP receptor kinase family have been useful for probing physiologic functions of BMP signaling in vitro and in vivo and may have roles in the treatment of BMP-mediated diseases

which could be reversed by both ATM siRNA and Chk1 siRNA

Saracatinib

STAT3-IN-3 - CAS# 2361304-26-7 Catalog No.:M12094-10 CK-636 inserts into the hydrophobicSTAT3 IN 3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3), with anti proliferative activity. STAT3 IN 3 induces apoptosis in breast cancer cells. STAT3 IN 3 acts as a promising mitochondria targeting STAT3 inhibitor for cancer research. Product information CAS Number: 2361304 26 7 Molecular Weight: 600. 48 Formula: C27H26BrN3O6S Chemical Name: 4 bromo 2 {4 [7 (diethylamino) 2 oxo 2H chromene 3

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