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SAR-260093
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells
O-Desmethyl PKC412
Chemical Name: 6-(2-(tert-butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline
FH535 - CAS# 108409-83-2 size:2mg solid SAR-260093FH535, CAS No. 108409 83 2, is a catenin pathway inhibitor. FH535 represses pancreatic cancer xenograft growth and angiogenesis. FH535 increases the radiosensitivity and reverses epithelial to mesenchymal transition of radioresistant esophageal cancer cell line KYSE 150R. FH535 inhibited metastasis and growth of pancreatic cancer cells. FH535 selectively inhibits cell proliferation and potentiates imatinib induced apoptosis in myeloid leukemia cell
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