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PubMed Central PMCID: PMC2975629
It shows modest general cytotoxicity
increases β-cell mass and insulin content
Wargent ET
Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60268 PubMed Central PMCID: PMC2975629Y 27632, CAS No. 146986 50 7, is a widely used, selective inhibitor of the Rho associated protein kinase p160ROCK with a Ki value at ~ 0. 14 M. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self renewal properties, including hESC iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells. Product information CAS