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MC-VC-PABC-Aur0101 12525 PubMed Central PMCID: PMC4146675

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Description

PubMed Central PMCID: PMC4146675

InChiKey: JVLBGBDQWIMMLO-FQEVSTJZSA-N

15-31)23(26)19(32)14-29(21

IL-1β and TNFα (IC50 = 59

MC-VC-PABC-Aur0101 12525 PubMed Central PMCID: PMC4146675MC VC PABC Aur0101 is a drug linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC VC PABC. Product information CAS Number: 1438849 92 3 Molecular Weight: 1341. 66 Formula: C68H100N12O14S Chemical Name: {4 [(2S) 5 (carbamoylamino) 2 [(2S) 2 [6 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)hexanamido] 3 methylbutanamido]pentanamido]phenyl}methyl N (1 {[(1S) 1 {[(3R,4S,5S) 3

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