AT-56 46-8443 but highly potent against ROCK1

but highly potent against ROCK1 (IC50=100 nM)

Molecular Weight: 811

ClH/c1-2-28-20(25)23-10-9-16(13-23)12-22(11-15-3-5-17(21)6-4-15)14-18-7-8-19(29-18)24(26)27

5-a]pyrimidin-7-yl]phenyl]-N-methylacetamide

AT-56 46-8443 but highly potent against ROCK1AT 56 is an orally active and selective inhibitor of lipocalin type prostaglandin (PG) D synthase (L PGDS) with Ki of 75 M and IC50 of 95 M. Product information CAS Number: 162640 98 4 Molecular Weight: 397. 52 Formula: C25H27N5 Chemical Name: 4 (5H dibenzo[a,d]cyclohepten 5 ylidene) 1 [4 (2H tetrazol 5 yl)butyl] piperidine Smiles: C1CN(CCCCC2=NNN=N2)CCC1=C1C2=CC=CC=C2C=CC2=CC=CC=C21 InChiKey: LQNGMDUIRLSESZ UHFFFAOYSA N InChi: InChI=1S C25H27N5 c1 3