R-1479 Size:Solid 2 mg Chemical Name: 4-fluoro-2-(4-{[(3S

Chemical Name: 4-fluoro-2-(4-{[(3S

Chemical Name: N-(3-Chloro-1H-indol-7-yl)-1

The purpose of this study was to investigate the influence of small doses of both metabolites (0

RO 5185426 RO5185426 Vemurafenib

R-1479 Size:Solid 2 mg Chemical Name: 4-fluoro-2-(4-{[(3SR 1479, also known as 4' azidocytidine, is a potent inhibitor of NS5B dependent RNA synthesis and hepatitis C virus replication in cell culture. R 1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC(50) = 1. 28 microM). The corresponding 5' triphosphate derivative (R1479 TP) is a potent inhibitor of native HCV replicase isolated from replicon cells and of recombinant HCV polymerase (NS5B) mediated RNA synthesis