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Ropivacaine - CAS# 84057-95-4 3173 Smiles: CN([C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@@H](CC1C=CC=CC=1)C[C@H](C)C(O)=O)C(C)C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)[C@@H](C)CC

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Description

Smiles: CN([C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@@H](CC1C=CC=CC=1)C[C@H](C)C(O)=O)C(C)C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)[C@@H](C)CC

YS-49 (10-100 μM

inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo

Chemical Name: 6-(prop-2-yn-1-yloxy)-1-(propan-2-yl)-4-[4-(propan-2-yl)phenyl]-1

Ropivacaine - CAS# 84057-95-4 3173 Smiles: CN([C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@@H](CC1C=CC=CC=1)C[C@H](C)C(O)=O)C(C)C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)[C@@H](C)CCRopivacain is a potent sodium channel blocker and acts as a local anesthetic agent. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two pore domain potassium channel) TREK 1 with an IC50 of 402. 7 M in COS 7 cell's membrane. Ropivacaine is used for the research of regional anesthesia and neuropathic pain management. Product information CAS Number: 84057 95 4

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