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Evaluation in mouse
Indirubin blocks the phosphorylation and degradation of IκBα through the inhibition of activation of IκBα kinase and phosphorylation and nuclear translocation of p65
Smiles: CC1=CC=CC(=N1)C1=NN2CCCC2=C1C1=CC=NC2=CC=C(C=C12)C(N)=O
Formula: C17H15ClO4
X-NeuNAc Size:Solid 10 mg Evaluation in mouseX NeuNAc, also known as CB1339 and X Neu5Ac, is a novel substrate for chromogenic assay of neuraminidase activity in bacterial expression systems. X NeuNAc can be used to facilitate the screening of bacterial colonies or plaques for the detection of either natural or mutant neuraminidase activity. Preliminary kinetic studies indicate that this compound is a good substrate (Km 0. 89 x 10( 3) M) for neuraminidase and is quite stable under identical