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ML277 is the first selective and potent activator found
MCF-7 cells) inhibits cells proliferation
OSI-027 was used at 1-10 µM in vitro and in cellular assays
Formula: C25H32N2O7
Mal-NH-Boc 798MH-233 ML277 is the first selectiveMal NH Boc is an alkyl ether based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 134272 63 2 Molecular Weight: 240. 26 Formula: C11H16N2O4 Chemical Name: tert butyl N [2 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)ethyl]carbamate Smiles: CC(C)(C)OC(=O)NCCN1C(=O)C=CC1=O InChiKey: SNYRFQCLCLMCCG UHFFFAOYSA N InChi: InChI=1S C11H16N2O4 c1 11(2,3)17 10(16)12 6 7 13 8(14)4 5 9(13)15 h4 5H,6 7H2,1 3H3,(H,12,16)
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