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Hit-to-lead studies: The discovery of potent
PubMed PMID: 22941213
2017 Feb 3
(2008) J Med Chem
R-268712 - CAS# 879487-87-3 157 Hit-to-lead studies: The discovery ofR 268712, CAS No. 879487 87 3, is a specific inhibitor of activin receptor like kinase 5 (ALK5). It is also an orally active transforming growth factor type I receptor inhibitor. Product information CAS Number: 879487 87 3 Molecular Weight: 363. 39 Formula: C20H18FN5O Chemical Name: 2 [4 [2 Fluoro 5 [3 (6 methylpyridine 2 yl) 1H pyrazol 4 yl] phenyl] pyrazol 1 yl]ethanol Smiles: CC1=CC=CC(=N1)C1=NNC=C1C1=CC(=C(F)C=C1)C1C=NN(CCO)C=1 InChiKey:
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