Safingol Catalog No.:M22674-C OC(=O)C1=CC2=C(C=C1)NC=C2CCCCN1CC=C(CC1)C1C=CC=CC=1

OC(=O)C1=CC2=C(C=C1)NC=C2CCCCN1CC=C(CC1)C1C=CC=CC=1

351(3):674-84

InChiKey: SCULJPGYOQQXTK-OLRINKBESA-N

Formula: C27H29ClN2O4S2

Safingol Catalog No.:M22674-C OC(=O)C1=CC2=C(C=C1)NC=C2CCCCN1CC=C(CC1)C1C=CC=CC=1Ki: SphK with a Ki of about 5 mol L Safingol is a sphingosine and PKC kinases inhibitor. Sphingosine 1 phosphate, a product of sphingosine kinases (SphK), mediates various biological processes including cell proliferation, differentiation, motility, and apoptosis. Protein kinase C (PKC), is a family of protein kinase enzymes involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine