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InChi: InChI=1S/C21H20N4O/c1-2-7-17(8-3-1)10-11-19-21(26-16-15-25-13-4-5-14-25)24-18-9-6-12-22-20(18)23-19/h1-3
1% and G1 cell cycle arrest with cells in G1 phase increasing from 42
Chemical Name: 2-(3-(4-(7H-pyrrolo[2
corresponding to 120 mg/kg of free base) significantly blockes growth of tumors compared with vehicle treatment alone with no change in body weight
PROTAC BRD4-binding moiety 1 - CAS# 2101200-10-4 Size:contact [email protected] InChi: InChI=1S/C21H20N4O/c1-2-7-17(8-3-1)10-11-19-21(26-16-15-25-13-4-5-14-25)24-18-9-6-12-22-20(18)23-19/h1-3PROTAC BRD4 binding moiety 1 is a ligand for BRD4. PROTAC BRD4 binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY 133136). Product information CAS Number: 2101200 10 4 Molecular Weight: 371. 43 Formula: C23H21N3O2 Chemical Name: 6 (3, 5 dimethyl 1, 2 oxazol 4 yl) 1 methyl 4 phenyl 3 (prop 2 yn 1 yl) 1, 2, 3, 4 tetrahydroquinazolin 2 one Smiles: CN1C(=O)N(CC#C)C(C2=CC(=CC=C12)C1=C(C)ON=C1C)C1=CC=CC=C1 InChiKey:
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