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OTX015 was used at 2-10 µM final concentration in various in vitro assays
InChi: InChI=1S/C16H19N3O5S
Treatment of MM cell lines with EZM 2302 leads to inhibition of PABP1 and SMB methylation and cell stasis with IC50 values in the nanomolar range (9
Clin Rheumatol
RuBi-Glutamate e Y (human) OTX015 was used at 2-10Product information CAS Number: 1220121 59 4 Molecular Weight: 970. 54 Formula: C28H32F12N5Na2O4P3Ru Chemical Name: ruthenium(2+) disodium bis(2,2' bipyridine) bis(hexafluoro phosphanuide) trimethylphosphane 2 aminopentanedioate Smiles: [Na+].[Na+].[Ru+2]. CP(C)C. NC(CCC([O ])=O)C([O ])=O. F[P ](F)(F)(F)(F)F. F[P ](F)(F)(F)(F)F. C1C=CC=NC=1C1=CC=CC=N1. C1C=CC=NC=1C1=CC=CC=N1 InChiKey: SQQVSHWHIPVYSZ UHFFFAOYSA L InChi: InChI=1S 2C10H8N2. C5H9NO4.
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