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Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity
Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von Hippel-Lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities
with antitumor and neuroprotective activity
Formula: C31H46ClN3O8
3-O-Methyldopa Size:Contact [email protected] for quotation Dopamine D2 receptor antagonist-1 is3 O Methyldopa (3 Methoxy L tyrosine) is a metabolite of L DOPA which is formed by catechol O methyltransferase (COMT). 3 O Methyldopa competitively inhibits the pharmacodynamics of l DOPA and dopamine. Product information CAS Number: 300 48 1 Molecular Weight: 211. 21 Formula: C10H13NO4 Chemical Name: (2S) 2 amino 3 (4 hydroxy 3 methoxyphenyl)propanoic acid Smiles: COC1=CC(C[C@H](N)C(O)=O)=CC=C1O InChiKey: PFDUUKDQEHURQC ZETCQYMHSA N InChi: InChI=1S
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