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Angiotensin 1-7 (Ang 1-7) abrogates the methylglyoxal-modified albumin (MGA)-stimulated myofibroblast phenotype by inhibiting the chronic stimulation of the TGF-β-ERK pathway in NRK-52E cells
InChi: InChI=1S/C26H23F4N9O/c27-20-18(1-7-32-22(20)26(28
6 nM for human SSTR5 Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene
InChiKey: KCBJGVDOSBKVKP-UHFFFAOYSA-N
PF-06835919 Catalog No.:M33609-C Angiotensin 1-7 (Ang 1-7) abrogatesPF 06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF 06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to
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