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Bis(dihydrochelerythrinyl)amine spium (chloride) S3I-201 (NSC-74859) preferentially inhibits Stat3

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Description

S3I-201 (NSC-74859) preferentially inhibits Stat3 DNA-binding activity over that of Stat1 (IC50 values

whereas 30 μM completely inhibited it

Treatment with 25 mg/Kg SC66 significantly reduces tumor volume to 37% on day 17 when compared with tumors of the untreated group

and A549 cells

Bis(dihydrochelerythrinyl)amine spium (chloride) S3I-201 (NSC-74859) preferentially inhibits Stat3Bis(dihydrochelerythrinyl)amine possesses anti bacteria activity. Product information CAS Number: 165393 48 6 Molecular Weight: 711. 76 Formula: C42H37N3O8 Chemical Name: N {17,18 dimethoxy 21 methyl 5,7 dioxa 21 azapentacyclo[11. 8. 0. 0,. 0,. 0,]henicosa 1,3,8,10,12,14,16,18 octaen 20 yl} 17,18 dimethoxy 21 methyl 5,7 dioxa 21 azapentacyclo[11. 8. 0. 0,. 0,. 0,]henicosa 1,3,8,10,12,14,16,18 octaen 20 amine Smiles:

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