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SPD304 has an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α
Animal tests using human tumour xenograft models demonstrates that E7070 can cause not only tumour growth suppression
Genetic evidence in both mice and humans demonstrates that Lck kinase activity is critical for signaling mediated by the T cell receptor (TCR)
InChi: InChI=1S/C24H27N3O4/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30/h5-14
m-PEG10-amine Size:Contact [email protected] for quotation SPD304 has an IC50 ofm PEG10 amine is a non cleavable 10 unit PEG ADC linker used in the synthesis of antibody drug conjugates (ADCs). m PEG10 amine is also a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1383658 09 0 Molecular Weight: 471. 58 Formula: C21H45NO10 Chemical Name: 2,5,8,11,14,17,20,23,26,29 decaoxahentriacontan 31 amine Smiles: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN InChiKey: JVILNPVFPORAFH UHFFFAOYSA N