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24 or 72 h) does not induce apoptosis of HCA-7 and LLC cells
which inhibits rat liver microsomal squalene synthase with an IC50 of 0
Solubility: DMSO : ≥ 150 mg/mL (321
Chemical Name: (6S)-5
(S)-Lisofylline Catalog No.:M22422-C 24 or 72 h) doesLisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,