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SMAP-2 significantly reduces abdominal aortic aneurysms (AAA) incidence and aortic dilation in pro-AAA apolipoprotein E-null (ApoE-/-) mice
InChiKey: WPYWMXNXEZFMAK-UHFFFAOYSA-N
InChi: InChI=1S/C22H21FN2O2S2/c1-12(2)27-21(26)19-15-8-5-9-18(15)29-20(19)25-22(28)24-17-11-10-16(23)13-6-3-4-7-14(13)17/h3-4
brain-penetrant and orally active GP130 receptor agonist
SIRT-IN-3 Catalog No.:M28189-C SMAP-2 significantly reduces abdominal aorticSIRT IN 3 is a potent SIRT inhibitor, with an IC50 of 17 M for SIRT1. SIRT IN 3 shows about 4 fold and 14 fold selectivity for SIRT1 over SIRT2 and SIRT3, respectively (IC50 of 74 M and 235 M for SIRT2 and SIRT3, respectively). Product information CAS Number: 1211 19 4 Molecular Weight: 212. 25 Formula: C13H12N2O Chemical Name: 2 (phenylamino)benzamide Smiles: NC(=O)C1=CC=CC=C1NC1C=CC=CC=1 InChiKey: JKWQUMKCVDUICQ UHFFFAOYSA N InChi: InChI=1S
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