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CCG-63808 metabolite Hydroxy Iloperidone PubMed Central PMCID: PMC2791573

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Description

PubMed Central PMCID: PMC2791573

2265-64-7 (Dexamethasone isonicotinate)

4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3

In contrast to the other antiplatelet drugs

CCG-63808 metabolite Hydroxy Iloperidone PubMed Central PMCID: PMC2791573CCG 63808 is a potent and reversible RGS protein inhibitor. Regulators of G protein signalling (RGS) are major determinants of metabotropic receptor activity, reducing the lifespan of the GTP bound state of G proteins. Inhibition of spinal RGS4 restored endogenous analgesic signalling pathways and mitigated neuropathic pain. Signalling through CB1 receptors may be involved in this beneficial effect. Product information CAS Number: 620113 73 7

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