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PROTAC ERα Degrader-2 Catalog No.:M7993-2 and dose-dependently suppresses VEGF-induced survival

SKU: 62362641896

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Description

and dose-dependently suppresses VEGF-induced survival and migration of endothelial cells in the same dose range without cytotoxic or antiproliferative effect on cells that do not express VEGF receptors

Formula: C30H29N5O6S2

InChi: InChI=1S/C26H34N6O3S/c1-19-17-27-25(29-21-8-5-7-20(15-21)18-32-11-13-35-14-12-32)30-24(19)28-22-9-6-10-23(16-22)36(33

Biomol Ther (Seoul)

PROTAC ERα Degrader-2 Catalog No.:M7993-2 and dose-dependently suppresses VEGF-induced survivalPROTAC ER Degrader 2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor (ER) binding group. PROTAC ER Degrader 2 is an ER degrader. Maximal ER degradation at 30 M concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non genetic IAP dependent protein erasers (SNIPERs). Product information CAS Number: 1351169 29 3 Molecular Weight: 763. 96 Formula: C42H61N5O8 Chemical Name:

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