OT-R antagonist 1 798rterolane with a Ki of 8

with a Ki of 8

BRD9757 was suggested to be used at 10 µM final concentration in vitro and in cellular assays

Hedegaard A

is a formyl peptide receptor 1 (FPR1) antagonist

OT-R antagonist 1 798rterolane with a Ki of 8OT R antagonist 1 is a new potent and selective nonpeptide low molecular weight OT R antagonist. OT R antagonist 1 inhibits oxytocin evoked intracellular Ca2+ mobilization (IC50 = 8 nM). IC50 value: 8 nMTarget: oxytocin receptorin vitro: OT R antagonist 1 inhibitis IP3 Synthesis, rat OT R (IC50=0. 03 uM). OT R antagonist 1 inhibits phosphodiesterase IV with IC50 = 6. 1 M, a value about 300 fold higher than the affinity for OT R. OT R antagonist 1