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BMS 961 Size:Contact [email protected] for quotation Formula: C27H40ClN5O4S

SKU: 62887526125

4.3
USD100.00 USD134.00

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Description

Formula: C27H40ClN5O4S

CAS Number: 114-26-1

The dose-effect curve of morphine for antinociception is shifted two- and threefold to the left in C57Bl/6 mice pretreated with HS014 TFA and in A(y) mice

InChi: InChI=1S/C23H26N6O2

BMS 961 Size:Contact [email protected] for quotation Formula: C27H40ClN5O4SBMS961 is a potent and selective retinoic acid receptor gamma (RAR) agonist with IC50 values of 30 nM. RAR belongs to the family of nuclear receptors which regulates transcription. RAR mediates the anti proliferative and apoptotic effects of retinoids in cancer cells such as neuroblastoma cells. RAR is the principal receptor that regulates RA mediated growth arrest in keratinocytes. In vitro, application of BMS961on mouse ear skin was found to cause a

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