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Formula: C29H34FN5O5
Tigloylgomisin P displays weak cytotoxicity against A549 cells (GI50=18
1186/1756-8722-6-79
EGFR or insulin receptor tyrosine kinases or MEK
Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation Formula: C29H34FN5O5Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP competitive second generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0. 9 nM and an IC50 of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dimesylate causes double stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti tumor activity. Product information CAS Number: 1234015
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