GSK-LSD1 - LSD1 Inhibitor. CAS# 2102933-95-7 0073 DASA-58 was used at 1-10

DASA-58 was used at 1-10 µM final concentration in various assays

Shipping Condition: Shipped under ambien

Bayoumi AH

1062368-24-4

GSK-LSD1 - LSD1 Inhibitor. CAS# 2102933-95-7 0073 DASA-58 was used at 1-10GSK LSD1, CAS No. 2102933 95 7, is a highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~16 nM, and is > 1000 fold selective over other closely related FAD utilizing enzymes (i. e. LSD2, MAO A, MAO B). GSK LSD1 induces gene expression changes in cancer cell lines (average EC50 < 5 nM) and inhibits cancer cell line growth (average EC50 < 5 nM). Product