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which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells
3 nM (human Cdc25A)
deltarasin inhibits the interaction of RAS with PDEδ with KD of 41 nM
Emodin is also shown to block cytomegalovirus infections as well as herpes simplex
Bis-PEG12-endo-BCN ltransferase which is potent PROTAC K-RasBis PEG12 endo BCN is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information Molecular Weight: 941. 15 Formula: C48H80N2O16 Chemical Name: bis(bicyclo[6. 1. 0]non 4 yn 9 ylmethyl) (3, 6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36 dodecaoxaoctatriacontane 1, 38 diyl)dicarbamate Smiles: O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1C2CCC#CCCC12)OCC1C2CCC#CCCC12 InChiKey: NJBQOQNHLPWBSB UHFFFAOYSA N InChi: InChI=1S
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