PROTAC K-Ras Degrader-1 Catalog No.:M21498-C Smiles: CC1C=C(C=C(C)C=1C1=CC(COC2C=CC(=CC=2)C2=CC(=O)NS2=O)=CC=C1)OCCCS(C)(=O)=O

Smiles: CC1C=C(C=C(C)C=1C1=CC(COC2C=CC(=CC=2)C2=CC(=O)NS2=O)=CC=C1)OCCCS(C)(=O)=O

SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that time (pKi=9

InChiKey: LSFLAQVDISHMNB-AFARHQOCSA-N

hypolipidemic and antitumor activities

PROTAC K-Ras Degrader-1 Catalog No.:M21498-C Smiles: CC1C=C(C=C(C)C=1C1=CC(COC2C=CC(=CC=2)C2=CC(=O)NS2=O)=CC=C1)OCCCS(C)(=O)=OPROTAC K Ras Degrader 1 (Compound 518) is potent K Ras degrader based PROTAC, exhibits 70% degradation efficacy in SW1573 cells. Product information CAS Number: 2378258 52 5 Molecular Weight: 999. 12 Formula: C53H62N10O10 Chemical Name: 2 [(2S) 4 (2 {[(2S,4R) 4 (2 {2 [2 (2 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4 yl]amino}ethoxy)ethoxy]ethoxy}ethoxy) 1 methylpyrrolidin 2 yl]methoxy} 7 (naphthalen 1 yl) 5H,6H,7H,8H pyrido[3,4