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paw edema was produced in CD-1 mice by the injection snake venom PLA2 into the hind paw
6R)-3-hydroxy-6-{[(1S
and its half inhibitory concentration for the growth of A549 cells was 15
082 nM (in membrane-assay/in cell-basedγ-secretase assays)) and also inhibits Notch clevage (IC50= 0
CCT 031374 hydrobromide Catalog No.:M22781-C paw edema was produced inCCT 031374 hydrobromide is a selective inhibitor of Wnt catenin signaling pathway . The Wnt catenin pathway is activated by the binding of Wnt ligand to a complex comprising LRP5 6 and Frizzled (Fz) receptors and then activates transcription factor catenin dependent transcription . CCT 031374 hydrobromide is a selective Wnt catenin signaling pathway inhibitor. CCT031374 inhibited BIO induced catenin accumulation in L cells with IC50 value of 6. 1 M.
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