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It shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases
reducing pro-hypertensive actions of angiotensin II
InChiKey: KKTZALUTXUZPSN-UHFFFAOYSA-N
Smiles: CC(C)(C#N)C1C=C(CN2C=NC=N2)C=C(C=1)C(C)(C)C#N
Proparacaine Hydrochloride - CAS# 5875-06-9 cylate It shows >63-fold selectivity forProparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. It is used as a topical ophthalmic anesthetic. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.
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