Larotrectinib sulfate 775riflophenone 3-C-glucoside and inhibits autophagy by impairing

and inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition

PF 3084014

Smiles: CN1CCN(CC1)C1C=CC(=CC=1)C1NC2=C(N=1)N=CC(Br)=C2N1CCN(CC2C=C(C)ON=2)CC1

4-tetrazol-1-yl]methyl}pyridine hydrochloride

Larotrectinib sulfate 775riflophenone 3-C-glucoside and inhibits autophagy by impairingLarotrectinib sulfate (LOXO 101 sulfate; ARRY 470 sulfate) is an ATP competitive oral, selective inhibitor of the tropomyosin related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). Product information CAS Number: 1223405 08 0 Molecular Weight: 526. 51 Formula: C21H24F2N6O6S Chemical Name: (3S) N {5 [(2R) 2 (2,5 difluorophenyl)pyrrolidin 1 yl]pyrazolo[1,5 a]pyrimidin 3 yl} 3