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Kumanogoh A
Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader
23)14-8-6-7-13(17)11(14)3/h6-8
BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25
NVS-SM2 Catalog No.:M15897-C Kumanogoh ANVS SM2 is a potent, orally active and brain penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS SM2 enhances U1 pre mRNA association. NVS SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS SM2 can be used for spinal muscular atrophy (SMA) research. Product information CAS Number: 1562333 92 9 Molecular Weight: 406. 52 Formula: C23H30N6O Chemical Name: 2 {6 [methyl(2,2,6,6
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