Pralsetinib Size:Contact [email protected] for quotation Smiles: C[C@@H](NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O

Smiles: C[C@@H](NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O

Peretinoin (10-40 μM

5 nM and 34 nM in canine and guinea pig left ventricular myocytes

34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3

Pralsetinib Size:Contact [email protected] for quotation Smiles: C[C@@H](NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=OPralsetinib (BLU 667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU 667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6 RET fusion with IC50s of 0. 4, 0. 3, 0. 4, 0. 4, and 0. 4 nM, respectively. Product information CAS Number: 2097132 94 8 Molecular Weight: 533. 60 Formula: C27H32FN9O2 Chemical Name: (1r,4r) N [(1S) 1 [6 (4 fluoro 1H pyrazol 1 yl)pyridin 3 yl]ethyl] 1 methoxy 4 {4 methyl 6 [(5 methyl 1H pyrazol 3