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EHMT2-IN-2 is a potent EHMT inhibitor
PubMed Central PMCID: PMC4703549
Chemical Name: 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'
Prexasertib Mesylate Hydrate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis
22(R)-hydroxy Cholesterol Catalog No.:M22746-C EHMT2-IN-2 is a potent EHMTEC50: 325 nM 22(R) hydroxy cholesterol is an endogenous agonist for liver X receptors (LXRs). The liver X receptors, LXRR and LXR, together with the farnesoid X receptor, FXR, form a subfamily of these orphan receptors. Recently, it has been reported that LXR and FXR are hormone receptors for oxysterols and bile acids, respectively. In vitro: Previous study found that 22(R) hydroxycholesterol was only found in the adrenals as an intermediate in
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